Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors

Aoxue Wang, Yejun Zou, Shuning Liu, Xiuze Zhang, Ting Li, Lijuan Zhang, Ruwen Wang, Yale Xia, Xie Li, Zhuo Zhang, Tiemin Liu, Zhenyu Ju, Ru Wang, Joseph Loscalzo, Yi Yang, Yuzheng Zhao

Published: 2024-02-02 DOI: 10.1038/s41596-023-00948-y

fluorescence imaging

lactate metabolism

FiLa biosensors

multiscale analysis

bioenergetic flux

AI 解读

Supplementary information

Supplementary Information

Supplementary Figs. 1–8.

Supplementary Data

Source data for Supplementary Figs. 1–7.

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Single-cell RNA sequencing (scRNA-seq)（单细胞RNA测序）

Data integration（数据集成）

Heterogeneity（异质性）

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Supplementary information

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Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors

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