Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells

Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Masaki Kimura, Asuka Kodaka, Shozo Nishii, Wendy L. Thompson, Takanori Takebe

Published: 2021-01-10 DOI: 10.1038/s41596-020-00441-w

organoids

pluripotent stem cells

hepato-biliary-pancreatic development

inter-organ connectivity

3D culture

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Human organoids are emerging as a valuable resource to investigate human organ development and disease. The applicability of human organoids has been limited, partly due to the oversimplified architecture of the current technology, which generates single-
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
- Reporting Summary
- References
References
- Procedure
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells

Supplementary information

Reporting Summary

Supplementary Video 1

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